HCID 68527206, compound → HCID 59252527, compound

HRID 237801Notes

Reaction equation

HRID 237801 reaction equation
[CH3:1][C:2]([C:9]1[CH:22]=[CH:21][C:12]([O:13][CH2:14][C@@H:15]2[O:19][C:18]([NH2:20])=[N:17][CH2:16]2)=[CH:11][CH:10]=1)([CH3:8])[CH2:3][C:4]([CH3:7])([CH3:6])[CH3:5]>C(Cl)(Cl)Cl>[CH3:8][C:2]([C:9]1[CH:22]=[CH:21][C:12]([O:13][CH2:14][C@@H:15]2[O:19][C:18]3=[N:20][C:12](=[O:13])[CH:11]=[CH:10][N:17]3[CH2:16]2)=[CH:11][CH:10]=1)([CH3:1])[CH2:3][C:4]([CH3:5])([CH3:6])[CH3:7]

Participants

3

Reactant 1

HCID 68527206HCID 68527206, compound

Product 1

HCID 59252527HCID 59252527, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

The title compound was prepared from (R)-5-(4-(1,1,3,3-tetramethyl-butyl) -phenoxymethyl)-4,5-dihydro-oxazol-2-ylamine employing the procedures as set forth in Step 3 of Example 1. [α]D25 −45.23 (c 0.489, CHCl3).

Sources & evidence

ORD record
ord-ac1fa365798d4bcb8348c6ccf9dc9353
Source dataset
uspto-grants-2014_02
Patent number
US08642603B2

Reaction notes

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