HCID 67061044, compound → HCID 59252491, compound

HRID 237803Notes

Reaction equation

HRID 237803 reaction equation
[C:1]([C:5]1[CH:18]=[CH:17][C:8]([O:9][CH2:10][C@@H:11]2[O:15][C:14]([NH2:16])=[N:13][CH2:12]2)=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2]>C(Cl)(Cl)Cl>[C:1]([C:5]1[CH:18]=[CH:17][C:8]([O:9][CH2:10][C@@H:11]2[O:15][C:14]3=[N:16][C:8](=[O:9])[CH:7]=[CH:6][N:13]3[CH2:12]2)=[CH:7][CH:6]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 1

HCID 67061044HCID 67061044, compound

Product 1

HCID 59252491HCID 59252491, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

The title compound was prepared from (R)-5-(4-tert-butyl-phenoxymethyl)-4,5-dihydro-oxazol-2-ylamine employing the procedures as set forth in Step 3 of Example 1. [α]D25 +52.20 (c 0.5, CHCl3).

Sources & evidence

ORD record
ord-dcbbb7f9483b4599ac525db686c0fea9
Source dataset
uspto-grants-2014_02
Patent number
US08642603B2

Reaction notes

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