Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2378036Generated: October 30, 2026

8-Quinolinecarboxylic acid → (RS)-1-(2-Benzo[b]thiophen-2-ylmethyl-piperidin-1-yl)-1-quinolin-8-yl-methanone

https://huagongshe.com/reaction/2378036

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-Quinolinecarboxylic acidHCID 66582—
ReactantHCID 23146368HCID 23146368—
Product(RS)-1-(2-Benzo[b]thiophen-2-ylmethyl-piperidin-1-yl)-1-quinolin-8-yl-methanoneHCID 231463781.8%

Reaction Steps

The title compound (4 mg) was prepared from 2-benzo[b]thiophen-2-ylmethyl-piperidine D83(133 mg) and 8-quinoline carboxylic acid (109 mg) according to a procedure similar to that described for Example 4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07470710B2
Source datasetuspto-grants-2008_12
ORD IDord-2407f7954770498e8d4faaceb66395dc
Source noteuspto-grants-2008_12