Pyridine → HCID 58599184, compound

Participants

Reaction Steps

1-Napthalene-methylamine (1.118 g, 7.11 mmol) was dissolved in THF before pyridine (1.725 ml, 21.3 mmol) was added. 4-Acetyl-benzenesulfonyl chloride (1.554 g, 7.11 mmol) was then added as a solid, and the resulting dark solution was stirred for 10 minutes. The volatiles were then removed, and the resulting residue was suspended in THF. Excess Et3N was then added, and the mixture was stirred for several minutes before the solids were filtered. The mother liquor was then evaporated to a solid which was recrystalized in ethylacetate and hexanes to yield 0.5697 g (0.00167 mol, 23%) of desired compound that was pure enough for the next step. LC-MS (ES+): 340 [MH]+ m/e.

Provenance & Evidence