HCID 68527064, compound → HCID 59252493, compound

HRID 237805Notes

Reaction equation

HRID 237805 reaction equation
[CH:1]1([C:7]2[CH:20]=[CH:19][C:10]([O:11][CH2:12][C@@H:13]3[O:17][C:16]([NH2:18])=[N:15][CH2:14]3)=[CH:9][CH:8]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1>C(Cl)(Cl)Cl>[CH:1]1([C:7]2[CH:20]=[CH:19][C:10]([O:11][CH2:12][C@@H:13]3[O:17][C:16]4=[N:18][C:10](=[O:11])[CH:9]=[CH:8][N:15]4[CH2:14]3)=[CH:9][CH:8]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 1

HCID 68527064HCID 68527064, compound

Product 1

HCID 59252493HCID 59252493, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

The title compound was prepared from (R)-5-(4-cyclohexyl-phenoxymethyl)-4,5-dihydro-oxazol-2-ylamine employing the procedures as set forth in Step 3 of Example 1. [α]D25 +52.40 (c 0.5, CHCl3).

Sources & evidence

ORD record
ord-875a11542da7414099645f1aefb715cf
Source dataset
uspto-grants-2014_02
Patent number
US08642603B2

Reaction notes

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