HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21314826, compound → HCID 58608299, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21314826 | HCID 21314826 | — |
| Reactant | 7-formyl-1-methyl-1H-indole-2-carboxylic acid (5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenyl)-amide | HCID 59856611 | — |
| Product | HCID 58608299 | HCID 58608299 | — |
Reaction Steps
Piperazine-1-carboxylic acid 2,2,2-trichloro-ethyl ester and 7-formyl-1-methyl-1H-indole-2-carboxylic acid (5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenyl)-amide were reacted under the reductive amination conditions described in Example 2 to provide the desired 4-[2-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenylcarbamoyl)-1-methyl-1H-indol-7-ylmethyl]-piperazine-1-carboxylic acid 2,2,2-trichloro-ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07470692B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-80c8e3e951844bc8ab7cf80f8e43f7f6 |
| Source note | uspto-grants-2008_12 |