Trifluoroacetic acid → HCID 11699961, compound

Participants

Reaction Steps

To a solution of 4-[2-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenylcarbamoyl)-1-methyl-1H-indol-7-yloxy]-piperidine-1-carboxylic acid tert-butyl ester (160 mg, 0.254 mmol) (Example 7) in dichloromethane (1 mL) was added trifluoroacetic acid (0.2 mL). The mixture was stirred at room temperature overnight and concentrated. The crude piperidine intermediate thus obtained was dried under vacuum and directly used in later reactions.

Provenance & Evidence