Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Benzyloxy-4-(3,3,5,5-tetramethyl-cyclohex-1-enyl)-benzene → 4-(3,3,5,5-Tetramethyl-cyclohexyl)-phenol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Benzyloxy-4-(3,3,5,5-tetramethyl-cyclohex-1-enyl)-benzene | HCID 68525815 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 4-(3,3,5,5-Tetramethyl-cyclohexyl)-phenol | HCID 68525863 | 96.6% |
반응 단계
To 10% Pd/C (0.17 g) under N2 was added 1-benzyloxy-4-(3,3,5,5-tetramethyl-cyclohex-1-enyl)-benzene (1.7 g, 5.3 mmol), prepared by a substantially similar procedure to that of Step 1 of Example 18, in MeOH (15 mL) and EtOAc (15 mL). This mixture was stirred under H2 (1 atm) overnight. The reaction mixture was filtered through celite. The filtrate was concentrated to give the title compound as a white solid (1.19 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08642603B2 |
| 출처 데이터셋 | uspto-grants-2014_02 |
| ORD ID | ord-8b5b782ad61043aab7f5d69373edc6f7 |
| 출처 메모 | uspto-grants-2014_02 |