Beta-Propiolactone → HCID 58838647, compound

HRID 2378145Notes

Reaction equation

HRID 2378145 reaction equation
[C:1]1(=[O:7])[O:6][CH2:5][CH2:4][CH2:3][CH2:2]1.Br[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH:15]=[CH2:16].C1(=O)OCC1.C([NH-])C=C>>[CH2:16]([CH:2]1[CH2:3][CH2:4][CH2:5][O:6][C:1]1=[O:7])[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH:10]=[CH2:9]

Participants

5

Reactant 4

HCID 2365Beta-PropiolactoneHCID 10953Delta-ValerolactoneHCID 759078-Bromooct-1-eneHCID 53627781HCID 53627781, compound

Product 1

HCID 58838647HCID 58838647, compoundYield 63%

Procedure

13.25 g of tetrahydro-3-(7-octenyl)-2H-pyrane-2-one of interest was prepared in the same manner as in Example 1 except that 10.01 g (100.0 mmol) of δ-valerolactone and 22.93 g (110.0 mmol) of 8-bromo-1-octene were used instead of β-propiolactone and allyl amide described in Preparation Example 1.

Workup

  1. customdescribed in Preparation Example 1

Sources & evidence

ORD record
ord-13f695587eee4b7db0698e9c0577f545
Source dataset
uspto-grants-2008_12
Patent number
US07470768B2

Reaction notes

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