Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Cyclohexenyl trifluoromethanesulfonate → 1-Cyclohex-1-enyl-2-isopropyl-4-methoxy-benzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Cyclohexenyl trifluoromethanesulfonate | HCID 319440 | — |
| 반응물 | 2-Isopropyl-4-methoxyphenyl boronic acid | HCID 22021769 | — |
| 생성물 | 1-Cyclohex-1-enyl-2-isopropyl-4-methoxy-benzene | HCID 68529260 | — |
| 생성물 | Cyclohexyl-4-methoxy-2-isopropyl-benzene | HCID 68529356 | — |
반응 단계
Cyclohexyl-4-methoxy-2-isopropyl-benzene was prepared in two steps by a Suzuki coupling of 4-methoxy-2-isopropyl-phenylboronic acid and cyclohexenol triflate following the procedures of Carmen et. al., Synlett 2005, No. 10, pp 1601-1605, to obtain 1-cyclohex-1-enyl-2-isopropyl-4-methoxy-benzene, which was subsequently hydrogenated (Pd/C, H2, MeOH) to form 1-cyclohexyl-4-methoxy-2-isopropyl-benzene.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08642603B2 |
| 출처 데이터셋 | uspto-grants-2014_02 |
| ORD ID | ord-e6a36dbe029b450e83c3f8c4e7ba5dac |
| 출처 메모 | uspto-grants-2014_02 |