HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl pent-2-yn-1-oate → (S)-2-(4-tert-Butyl-phenoxymethyl)-5-ethyl-2,3-dihydro-oxazolo[3,2-a]pyrimidin-7-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl pent-2-yn-1-oate | HCID 99169 | — |
| Reactant | (S)-5-(4-tert-butyl-phenoxymethyl)-4,5-dihydro-oxazol-2-ylamine | HCID 67060987 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | (S)-2-(4-tert-Butyl-phenoxymethyl)-5-ethyl-2,3-dihydro-oxazolo[3,2-a]pyrimidin-7-one | HCID 25073613 | — |
Reaction Steps
The title compound was prepared from (S)-5-(4-tert-butyl-phenoxymethyl)-4,5-dihydro-oxazol-2-yl-amine and ethyl 2-pentynoate according to the procedures employed for the preparation of the compound in Example 95. [α]D25 −29.20 (c 0.5, CHCl3)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642603B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-4ba305e817224b9487425d7d671ecf56 |
| Source note | uspto-grants-2014_02 |