HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxy-4-methyl-pent-2-ynoic acid ethyl ester → (S)-2-(4-Cyclohexyl-phenoxymethyl)-5-(1-hydroxy-1-methyl-ethyl)-2,3-dihydro oxazolo[3,2-a]pyrimidin-7-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxy-4-methyl-pent-2-ynoic acid ethyl ester | HCID 11228926 | — |
| Reactant | (S)-5-(4-cyclohexyl-phenoxymethyl)-4,5-dihydro-oxazol-2-ylamine | HCID 66875140 | — |
| Product | (S)-2-(4-Cyclohexyl-phenoxymethyl)-5-(1-hydroxy-1-methyl-ethyl)-2,3-dihydro oxazolo[3,2-a]pyrimidin-7-one | HCID 25073305 | — |
Reaction Steps
The title compound was prepared from (S)-5-(4-cyclohexyl-phenoxymethyl)-4,5-dihydro-oxazol-2-ylamine and 4-hydroxy-4-methyl-pent-2-ynoic acid ethyl ester employing the procedure described in Example 105.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642603B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-0e1180f4583148c28a53665811847086 |
| Source note | uspto-grants-2014_02 |