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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 237847Generated: October 25, 2026

Ethyl chloroformate → Ethyl 5-(tetrahydro-2H-pyran-2-yloxy)-2-pentynoate

https://huagongshe.com/reaction/237847

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl chloroformateHCID 10928—
Reactant2-(3-Butynyloxy)tetrahydro-2H-pyranHCID 142440—
ProductEthyl 5-(tetrahydro-2H-pyran-2-yloxy)-2-pentynoateHCID 365785—

Reaction Steps

The title compound was prepared from 2-but-3-ynyloxy-tetrahydro-pyran and ethyl chloroformate in accordance with the procedures of G. Cai et al., Tetrahedron, 2006, (5697-5708).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08642603B2
Source datasetuspto-grants-2014_02
ORD IDord-ddef041b63a14923a58fe31ec86684c1
Source noteuspto-grants-2014_02