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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 237848Generated: October 25, 2026

p-Toluenesulfonic acid → Ethyl 5-hydroxypent-2-ynoate

https://huagongshe.com/reaction/237848

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Toluenesulfonic acidHCID 6101—
ReactantEthyl 5-(tetrahydro-2H-pyran-2-yloxy)-2-pentynoateHCID 365785—
SolventEthanolHCID 702—
ProductEthyl 5-hydroxypent-2-ynoateHCID 15057368—

Reaction Steps

The title compound was prepared from 5-(tetrahydro-pyran-2-yloxy)-pent-2-ynoic acid ethyl ester employing p-toluenesulfonic acid in ethanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08642603B2
Source datasetuspto-grants-2014_02
ORD IDord-18fafd85b6f3414689c4ce92953b4a23
Source noteuspto-grants-2014_02