Triethylamine → HCID 68822387, compound

Participants

Reaction Steps

A mixture of 25 mg (0.1 mmol) of (16) and 17 μl (0.12 mmol) triethyl amine in 0.5 ml THF was treated at 0° C. with 21 μl (0.11 mmol) TMSOTf. After 30 min 8 μl (0.06 mmol) triethyl amine and 10 μl (0.055 mmol) TMSOTf were added. After 10 min the mixture was diluted with diethyl ether and was poured into 2 ml of a saturated NH4Cl solution. The organic phase was separated, diluted with 3 ml of dichloro methane and the solvent was evaporated at room temperature under vacuum to afford 32 mg (19) (yield: 99%).

Provenance & Evidence