N-bromobutanimide → HCID 22558899, compound

HRID 2378533Notes

Reaction equation

HRID 2378533 reaction equation
[CH:1]1([C:6]2[CH:11]=[CH:10][C:9]([CH2:12][CH2:13][C:14]([O:16][CH2:17][CH3:18])=[O:15])=[CH:8][C:7]=2[CH3:19])[CH2:5][CH2:4][CH2:3][CH2:2]1.C1C(=O)N([Br:27])C(=O)C1>>[Br:27][C:11]1[CH:10]=[C:9]([CH2:12][CH2:13][C:14]([O:16][CH2:17][CH3:18])=[O:15])[CH:8]=[C:7]([CH3:19])[C:6]=1[CH:1]1[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

3

Reactant 2

HCID 67184N-bromobutanimideHCID 22559106HCID 22559106, compound

Product 1

HCID 22558899HCID 22558899, compoundYield 95.7%

Procedure

According to the procedure described in the synthesis method of Compound No. A-1, Intermediate 15 (437 mg) and NBS (320 mg) were reacted and treated to obtain the title compound (Compound No. A-24, 545 mg).

Workup

  1. customdescribed in the synthesis method of Compound No
  2. additiontreated

Sources & evidence

ORD record
ord-d9273c80a40944bd878226721ecdf58a
Source dataset
uspto-grants-2008_12
Patent number
US07470807B2

Reaction notes

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