HRID237859

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID23234139

Ethyl 4-fluorobut-2-ynoate

C6H7FO2

结构：CC(C)(C)CC(C)(C)c1ccc(OC[C@@H]2CN=C(N)O2)cc1

HCID68529278

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)CC(C)(C)c1ccc(OC[C@@H]2Cn3c(CF)cc(=O)nc3O2)cc1

HCID59252486

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6212

Chloroform

CHCl3

PROCEDURE

实验过程

The title compound was prepared from (S)-5-(4-(1,1,3,3-tetramethyl-butyl) -phenoxymethyl)-4,5-dihydro-oxazol-2-ylamine (see Example 27) and 4-fluoro-but-2-ynoic acid ethyl ester (see Example 105) employing the procedure described in Example 95. [α]D25 −28.00 (c 0.5, CHCl3).