Dichloromethane → HCID 53653455, compound

Participants

Reaction Steps

Compound 155 (0.52 g, 51%) was prepared from 154 (1.5 g, 2.6 mmole), BCl3 (5M solution in CH2Cl2, 14 mL), CH2Cl2 (30 mL) and MeOH (20 mL) by the method described for 166 which on recrystallization from EtOAC gave 155: m.p. 155°; 1H NMR (DMSO-d6): d 5.76 (s, 2 H, C-1'), 4.63 t, 2 H, exchanges with D2O, 2×OH), 3.54-3.48 (m, 1 H, C-3'), PHACTS-PCS 3.43-3.25 (m, 4 H, C-4' and 5'H). Anal. Calcd. for C11H9N2Cl5O3 : C, 33.46; H, 2.28; N, 7.09. Found: C, 33.60; H, 2.15; N, 6.91.

Provenance & Evidence