2-Nitro-4-(trifluoromethyl)benzene-1-sulfonyl chloride → HCID 18957993, compound

HRID 2379098Notes

Reaction equation

HRID 2379098 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]([OH:18])([CH2:16][NH2:17])[CH2:10][N:11]1[CH:15]=[N:14][CH:13]=[N:12]1.[N+:19]([C:22]1[CH:27]=[C:26]([C:28]([F:31])([F:30])[F:29])[CH:25]=[CH:24][C:23]=1[S:32](Cl)(=[O:34])=[O:33])([O-:21])=[O:20]>>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]([OH:18])([CH2:16][NH:17][S:32]([C:23]1[CH:24]=[CH:25][C:26]([C:28]([F:30])([F:31])[F:29])=[CH:27][C:22]=1[N+:19]([O-:21])=[O:20])(=[O:33])=[O:34])[CH2:10][N:11]1[CH:15]=[N:14][CH:13]=[N:12]1

Participants

3

Reactant 2

HCID 27757802-Nitro-4-(trifluoromethyl)benzene-1-sulfonyl chlorideHCID 147065211-[3-Amino-2-(2,4-dichlorophenyl)-2-hydroxyprop-1-yl]-1H-1,2,4-triazole

Product 1

HCID 18957993HCID 18957993, compound

Procedure

Following the procedure described in the preceeding examples but using 2-(2,4-dichlorophenyl)-3-amino-1-(1H-1,2,4-triazol-1-yl)propan-2-ol and 2-nitro-4-trifluromethylbenzenesulfonylchloride, the title com-pound was obtained in a similar yield:

Workup

  1. customthe title com-pound was obtained in a similar yield

Sources & evidence

ORD record
ord-8387a6edd4c84d97990e6322afb95905
Source dataset
uspto-grants-1994_11
Patent number
US05360813

Reaction notes

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