HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 18958006, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 1H-1,2,4-Triazole, 1-[[2-(2,4-dichlorophenyl)oxiranyl]methyl]- | HCID 10423229 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 18958006 | HCID 18958006 | — |
Reaction Steps
A solution containing 2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)oxirane (5.5 g, 20.4 mmol), obtained as explained in EP 106515, a 40% solution of methylamine in ethanol (60 mL) and ethanol is stirred at 100° C. for 16 h in a closed vessel. The product is isolated by flash chromatography as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05360813 |
| Source dataset | uspto-grants-1994_11 |
| ORD ID | ord-c558589a5b3f42a29ded6be933dad6ed |
| Source note | uspto-grants-1994_11 |