HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2379117Generated: November 1, 2026
Hydrogen Bromide → 2-Bromo-4-fluoro-6-nitroaniline
https://huagongshe.com/reaction/2379117
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 4-Fluoro-2-nitroaniline | HCID 67769 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Bromo-4-fluoro-6-nitroaniline | HCID 292004 | — |
Reaction Steps
Mix 4-fluoro-2-nitroaniline (15.6g, 0.1mol) in water (400mL) and add 48% hydrobromic acid (1kg). Add bromine (16g, 0.1mol) with stirring and stir for 1 hour. Dilute to 2L and cool to 7° C. Filter, wash with water and dry to give 4-fluoro-2-bromo-6-nitroaniline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05360814 |
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| Source dataset | uspto-grants-1994_11 |
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| ORD ID | ord-e2ccd44dd28f4feb9477d70141d2c68b |
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| Source note | uspto-grants-1994_11 |
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