Ethanol → HCID 18957926, compound

Participants

Reaction Steps

A mixture of 4a (170 mg, 0.59 mmol), conc. sulfuric acid (3 mg, 0.029 mmol), and 99% ethanol (10 ml) was refluxed for 1 h. Silica gel was added to the mixture and the solvent was evaporated. The silica gel containing the crude product was put on top of a silica gel column and the product was eluated by methylene chloride/ethanol (9:1). Yield 120 mg, mp>360° C.

Provenance & Evidence