HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine → 3-(1,4,4,6-Tetramethyl-2,3,7-trioxacycloheptyl)propionhydrazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | Ethyl levulinate | HCID 10883 | — |
| Reactant | HCID 19380021 | HCID 19380021 | — |
| Catalyst | 4-Hydroperoxy-4-methylpentan-2-ol | HCID 15790339 | — |
| Product | 3-(1,4,4,6-Tetramethyl-2,3,7-trioxacycloheptyl)propionhydrazide | HCID 19380044 | 88% |
Reaction Steps
3-(1,4,4,6-Tetramethyl-2,3,7-trioxacycloheptyl)propionhydrazide was prepared by reacting 3-(ethoxycarbonylethyl)-3,5,7,7-tetramethyl-1,2,4-trioxacycloheptane with 9 molar excess of 54% aqueous hydrazine. 3-(Ethoxycarbonylethyl)-3,5,7,7-tetramethyl-1,2,4-trioxacycloheptane was initially prepared in an assay of 89% and a corrected yield of 88% by reacting ethyl levulinate with 10% molar excess of 3-hydroxy-1,1-dimethylbutyl hydroperoxide using 70% aqueous sulfuric acid as a catalyst/dehydrating agent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05360867 |
| Source dataset | uspto-grants-1994_11 |
| ORD ID | ord-f246f8bc3f0843389bc99ee299094aa1 |
| Source note | uspto-grants-1994_11 |