(1H-pyrrolo[3,2-b]pyridin-2-yl)methanol → HCID 18958302, compound
Reaction equation
O[CH2:2][C:3]1[NH:4][C:5]2[C:10]([CH:11]=1)=[N:9][CH:8]=[CH:7][CH:6]=2.Cl.[CH3:13][N:14](CC1NC2C(N=1)=NC=CC=2)[CH3:15]>>[CH3:13][N:14]([CH2:2][C:3]1[NH:4][C:5]2[C:10]([CH:11]=1)=[N:9][CH:8]=[CH:7][CH:6]=2)[CH3:15]Participants
3
Procedure
2-Dimethylaminomethyl-4-azaindole is synthesized from 2-hydroxymethyl-4-azaindole by a procedure analogous to that described for the synthesis of 2-dimethylaminomethyl-1H-imidazo[4,5-b]pyridine monohydrochloride in the J. Het. Chem., 6, 759-760 (1969).
Sources & evidence
- ORD record
- ord-1a97157990074fb58245591b8ad81ab9
- Source dataset
- uspto-grants-1994_11
- Patent number
- US05360907
Reaction notes
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