Pyridine → HCID 22981477, compound

HRID 2379308Notes

Reaction equation

HRID 2379308 reaction equation
[CH:1]([NH:3][C@H:4]([C:7]([OH:9])=O)[CH2:5][OH:6])=[O:2].[F-:10].N1[CH:16]=[CH:15][CH:14]=CC=1.[CH2:17](Cl)Cl>>[CH:1]([NH:3][C@H:4]([C:5]([F:10])=[O:6])[CH2:7][O:9][C:15]([CH3:14])([CH3:16])[CH3:17])=[O:2]

Participants

5

Reactant 4

HCID 1049PyridineHCID 6344DichloromethaneHCID 28179Fluoride IonHCID 54343585HCID 54343585, compound

Product 1

HCID 22981477HCID 22981477, compound

Procedure

N-formyl serine (1 mmole) in dry CH2Cl2 under nitrogen is treated with cyannuric fluoride (8 mmol) and pyridine (1 mmol) to form the above-identified product.

Workup

  1. customto form the above-identified product

Sources & evidence

ORD record
ord-20da87e2bb0c4972b3b41fad10c5a2b5
Source dataset
uspto-grants-1994_11
Patent number
US05360928

Reaction notes

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