1-(Trifluoromethylcarbonylaminosulphonyl)-3-nitrobenzene → 1-(Trifiuoromethyl carbonylaminosulphonyl)-3-aminobenzene

Participants

Reaction Steps

In the same way as that described in Example 11, Step 2, using 1-(trifluoromethylcarbonylaminosulphonyl)-3-nitrobenzene (2.7 g, 9.1 mmol), 10% palladium on carbon (0.25 g, 9% (w/w)) in water (3 ml) and ethanol (70 ml), the title compound (1.7 g, 70%) was afforded as a colourless solid. mp 106°-108° C. 1H NMR (360 MHz, D6 -DMSO) δ 6.59 (1H, m), 6.88 (1H, m), 7.02 (2H, m).

Provenance & Evidence