HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 5-[(3,4-Dihydroxy-5-nitrophenyl)methylidene]-2-thioxothiazolidin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | Rhodanine | HCID 1201546 | — |
| Reactant | 3,4-Dihydroxy-5-nitrobenzaldehyde | HCID 5748957 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 5-[(3,4-Dihydroxy-5-nitrophenyl)methylidene]-2-thioxothiazolidin-4-one | HCID 53862151 | — |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
A solution containing 2.1 g (0.0157 mol) of rhodanine, 2.76 g (0.0151 mol) of 3,4-dihydroxy-5-nitrobenzaldehyde and 0.15 ml of piperidine in 10 ml of acetic acid was heated for 7-8 h at 100° C. After cooling the crystalis were filtered and washed with 2-propanol. Yield 4.0 g (89%), mp>350° C. (decomp.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05362733 |
| Source dataset | uspto-grants-1994_11 |
| ORD ID | ord-b34af0f6becc4ce0a8ad600a544813d5 |
| Source note | uspto-grants-1994_11 |