HuagongsheHuagongshe Chemistry Print Report · For research reference only
Barbituric Acid → HCID 15292573, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Barbituric Acid | HCID 6211 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3,4-Dihydroxy-5-nitrobenzaldehyde | HCID 5748957 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 15292573 | HCID 15292573 | — |
Reaction Steps
To a solution containing 1.28 g (0.01 mol) of barbituric acid and 1.83 g (0.01 mol) of 3,4-dihydroxy-5-nitrobenzaldehyde in 20 ml of 2-propanol was gradually added 5.0 ml of thionyl chloride. The mixture was stirred for 100 h at room tempererature. The product was filtered, washed with 2-propanol and recrystallized from acetic acid. Yield 1.28 g (44%) , mp 269°-272° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05362733 |
| Source dataset | uspto-grants-1994_11 |
| ORD ID | ord-f43457983aaa4718836837bf8ba4c66a |
| Source note | uspto-grants-1994_11 |