Diisopropylethylamine → HCID 18957149, compound

Participants

Reaction Steps

When in the procedure of Example 1(f) an appropriate amount of (±)N-phenyl-2-[8-[(tetrahydro-2H-pyran-2-yl)oxy]octyl]-2H-tetrazol-5-amine was substituted for 2-dodecyl-N-phenyl-2H-tetrazol-5-amine, and reacted with triphosgene and 2,4,6-trimethoxyaniline hydrochloride in the presence of two equivalents of diisopropylethylamine, the title compound was obtained. 1H NMR (CDCl3): 8.7 (br s, 0.6H), 8.6 (br s, 0.4H), 7.4 (m, 5H), 6.2 (s, 2H), 4.6 (m, 1H), 4.5 (m, 2H), 3.8 (two s, 9H), 3.7 (m, 1H), 3.6 (t, 1H), 3.5 (m, 1H), 3.4 (m, 1H), 1.9 (m, 2H), 1.7-1.9 (m, 6H), 1.6 (m, 4H), 1.3 (m, 6H).

Provenance & Evidence