HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3,4-Dichlorophenyl)-4-piperidinol → 1-{3-(3,4-Dichlorophenoxy)propyl}-4-hydroxy-4-(3,4-dichlorophenyl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3,4-Dichlorophenyl)-4-piperidinol | HCID 18675728 | — |
| Reactant | 3-(3,4-Dichlorophenoxy)propylchloride | HCID 18768636 | — |
| Product | 1-{3-(3,4-Dichlorophenoxy)propyl}-4-hydroxy-4-(3,4-dichlorophenyl)piperidine | HCID 18957332 | 97.5% |
Reaction Steps
3-(3,4-dichlorophenoxy)propylchloride 1.38 g and 4-hydroxy-4-(3,4-dichlorophenyl)piperidine 1.35 g are reacted in the same manner as Example 109 (1) to prepare 2.40 g (Yield: 97.5%) of 1-{3-(3,4-dichlorophenoxy)propyl}-4-hydroxy-4-(3,4-dichlorophenyl)piperidine (III-66). mp. 118.0°-118.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05362873 |
| Source dataset | uspto-grants-1994_11 |
| ORD ID | ord-2b411f0316d24ec8972e104fb2fd525d |
| Source note | uspto-grants-1994_11 |