HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 3-Hydroxy-7,11,15-trimethylhexadeca-6,10,14-trienoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl 3-hydroxy-7,11,15-trimethylhexadeca-6,10,14-trienoate | HCID 53652710 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-Hydroxy-7,11,15-trimethylhexadeca-6,10,14-trienoic acid | HCID 53752372 | — |
Reaction Steps
A solution of methyl 3-hydroxy-7,11,15-trimethylhexadeca-6,10,14-trienoate (139 mg, 430 μmol), ethanol (1 mL) and sodium hydroxide (1N, 440 μL, 440 μmol) was stirred at room temperature for two-hours. The crude mixture was purified by flash chromatography on a 20 mm ID silica gel column. Elution of the column with choloform:acetic acid (40:1/v=v) gave title compound as a colorless gum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05362906 |
| Source dataset | uspto-grants-1994_11 |
| ORD ID | ord-d849200d1f1a4eb3b0e88577e2a46dbb |
| Source note | uspto-grants-1994_11 |