2,4,5-Trifluorobenzoic acid → 3-Chloro-2,4,5-trifluorobenzoic Acid

HRID 2379570Notes

Reaction equation

HRID 2379570 reaction equation
[Cl:1][C:2]1[C:3]([F:13])=[C:4]([CH:8]=[C:9]([F:12])[C:10]=1[F:11])[C:5](Cl)=[O:6].FC1C=C(F)C(F)=CC=1C(O)=[O:18]>>[Cl:1][C:2]1[C:3]([F:13])=[C:4]([CH:8]=[C:9]([F:12])[C:10]=1[F:11])[C:5]([OH:18])=[O:6]

Participants

3

Reactant 2

HCID 5211702,4,5-Trifluorobenzoic acidHCID 27822453-Chloro-2,4,5-trifluorobenzoyl chloride

Product 1

HCID 27342693-Chloro-2,4,5-trifluorobenzoic Acid

Procedure

A process for the preparation of 3-chloro-2,4,5-trifluorobenzoyl chloride, which comprises chlorinating 2,4,5-trifluorobenzoic acid to give 3-chloro-2,4,5-trifluorobenzoic acid, and reacting the latter with thionyl chloride.

Sources & evidence

ORD record
ord-79fdbce4cd51450c856d0bbab27a1c54
Source dataset
uspto-grants-1994_11
Patent number
US05362909

Reaction notes

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