4-Propylphenol → N-(Isoquinolin-5-yl)-2-(4-propylphenoxy)decanoic amide

HRID 2379604Notes

Reaction equation

HRID 2379604 reaction equation
[CH:1]1[C:10]2[C:5](=[C:6]([NH:11][C:12](=[O:23])[CH:13](Br)[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][N:2]=1.[CH2:24]([C:27]1[CH:32]=[CH:31][C:30]([OH:33])=[CH:29][CH:28]=1)[CH2:25][CH3:26]>>[CH:1]1[C:10]2[C:5](=[C:6]([NH:11][C:12](=[O:23])[CH:13]([O:33][C:30]3[CH:31]=[CH:32][C:27]([CH2:24][CH2:25][CH3:26])=[CH:28][CH:29]=3)[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][N:2]=1

Participants

3

Reactant 2

HCID 125804-PropylphenolHCID 14995543N-(isoquinolin-5-yl)-2-bromodecanoic amide

Product 1

HCID 14995411N-(Isoquinolin-5-yl)-2-(4-propylphenoxy)decanoic amide

Procedure

N-(isoquinolin-5-yl)-2-bromodecanoic amide, prepared according to the procedures described in Examples 3 and 25, was coupled with 4-propylphenol according to the procedure described in Example 6 to give the title compound.

Sources & evidence

ORD record
ord-2bc9b31f5a4c4479b5e1e26d414df842
Source dataset
uspto-grants-1994_11
Patent number
US05362878

Reaction notes

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