3-Aminoimidazo(1,2-a)pyridine → N-(Imidazo[1,2-a]pyridin-3-yl)-2-(4-(1-methylpropyl)phenoxy)nonanoic amide

HRID 2379612Notes

Reaction equation

HRID 2379612 reaction equation
[NH2:1][C:2]1[N:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]2=[N:4][CH:3]=1.[CH3:11][CH:12]([C:15]1[CH:32]=[CH:31][C:18]([O:19][CH:20]([CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[C:21](O)=[O:22])=[CH:17][CH:16]=1)[CH2:13][CH3:14]>>[N:4]1[CH:3]=[C:2]([NH:1][C:21](=[O:22])[CH:20]([O:19][C:18]2[CH:31]=[CH:32][C:15]([CH:12]([CH3:11])[CH2:13][CH3:14])=[CH:16][CH:17]=2)[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[N:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=12

Participants

3

Reactant 2

HCID 4322213-Aminoimidazo(1,2-a)pyridineHCID 149954072-(4-Sec-butylphenoxy)nonanoic acid

Product 1

HCID 14995434N-(Imidazo[1,2-a]pyridin-3-yl)-2-(4-(1-methylpropyl)phenoxy)nonanoic amide

Procedure

3-Aminoimidazo[1,2-a]pyridine, synthesized by reduction of the corresponding nitro compound according to Example 31, was coupled with 2-(4-(1-methylpropyl)- phenoxynonanoic acid according to the procedure of Example 25 to give the title compound.

Sources & evidence

ORD record
ord-c5b271e08f4c4cca9ed20606a79bec9b
Source dataset
uspto-grants-1994_11
Patent number
US05362878

Reaction notes

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