5-Amino-6-methylthioquinoline → N-(6-Methylthioquinolin-5-yl)-2-(4-sec-butylphenoxy)nonanoic amide

HRID 2379613Notes

Reaction equation

HRID 2379613 reaction equation
[NH2:1][C:2]1[C:11]([S:12][CH3:13])=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[N:7]2.[CH:14]([C:18]1[CH:35]=[CH:34][C:21]([O:22][CH:23]([CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])[C:24](O)=[O:25])=[CH:20][CH:19]=1)([CH2:16][CH3:17])[CH3:15]>>[CH3:13][S:12][C:11]1[C:2]([NH:1][C:24](=[O:25])[CH:23]([O:22][C:21]2[CH:34]=[CH:35][C:18]([CH:14]([CH2:16][CH3:17])[CH3:15])=[CH:19][CH:20]=2)[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])=[C:3]2[C:8](=[CH:9][CH:10]=1)[N:7]=[CH:6][CH:5]=[CH:4]2

Participants

3

Reactant 2

HCID 103976605-Amino-6-methylthioquinolineHCID 149954072-(4-Sec-butylphenoxy)nonanoic acid

Product 1

HCID 14995542N-(6-Methylthioquinolin-5-yl)-2-(4-sec-butylphenoxy)nonanoic amide

Procedure

5-Amino-6-methylthioquinoline, prepare as described in Example 34, was coupled with 2-(4-sec-butylphenoxy)nonanoic acid according to the procedure described in Example 25 to give the title compound.

Sources & evidence

ORD record
ord-2f6d88bbaebb49cd823dc46e69bc2841
Source dataset
uspto-grants-1994_11
Patent number
US05362878

Reaction notes

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