HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromooctane → N-(6-Methylthioquinolin-5-yl)-2-octanyl-1,3-dithiane-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromooctane | HCID 8140 | — |
| Reactant | 1,3-Dithiane-2-carboxylic acid | HCID 303705 | — |
| Reactant | Sodium bis(trimethylsilyl)amide | HCID 2724254 | — |
| Reactant | 5-Amino-6-methylthioquinoline | HCID 10397660 | — |
| Reactant | 2-Octanyl-1,3-dithiane-2-carboxylic acid | HCID 14995436 | — |
| Product | N-(6-Methylthioquinolin-5-yl)-2-octanyl-1,3-dithiane-2-carboxamide | HCID 14995437 | — |
Reaction Steps
5-Amino-6-methylthioquinoline, prepared as described in Example 34, was coupled with 2-octanyl-1,3-dithiane-2-carboxylic acid, prepared by treatment of 1,3-dithiane-2-carboxylic acid with sodiumhexamethyldisilazide and octanyl bromide, according to Example 25 to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05362878 |
| Source dataset | uspto-grants-1994_11 |
| ORD ID | ord-08b1aa7724ff459d8e809d0af70249e0 |
| Source note | uspto-grants-1994_11 |