2,4,6-Trimethoxyphenyl isocyanate → HCID 19027758, compound

HRID 2379618Notes

Reaction equation

HRID 2379618 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[C:5]([O:11][CH3:12])[C:4]=1[N:13]=[C:14]=[O:15].[CH3:16][C:17]([CH3:28])([CH3:27])[CH2:18][C:19]1[CH:26]=[CH:25][C:22]([CH2:23][NH2:24])=[CH:21][CH:20]=1>C(Cl)Cl>[CH3:12][O:11][C:5]1[CH:6]=[C:7]([O:9][CH3:10])[CH:8]=[C:3]([O:2][CH3:1])[C:4]=1[N:13]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])[C:14]([NH:24][CH2:23][C:22]1[CH:21]=[CH:20][C:19]([CH2:18][C:17]([CH3:28])([CH3:27])[CH3:16])=[CH:26][CH:25]=1)=[O:15]

Participants

4

Reactant 2

HCID 100818122,4,6-Trimethoxyphenyl isocyanateHCID 15115786HCID 15115786, compound

Product 1

HCID 19027758HCID 19027758, compoundYield 71%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The title compound was prepared according to the procedure of Example 97, but using 760 mg (3.63 mmole) 2,4,6-trimethoxyphenylisocyanate, 1.0 g (3.63 mmole) 4-(2,2-dimethylpropyl)benzylamine, and 20 ml methylene chloride. There was obtained 1.25 g product.

Sources & evidence

ORD record
ord-2e316405bfe844ac90beb3a305bac7aa
Source dataset
uspto-grants-1994_11
Patent number
US05362878

Reaction notes

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