Dichloroacetic Acid → HCID 19027775, compound

HRID 2379624Notes

Reaction equation

HRID 2379624 reaction equation
ClC(Cl)C(O)=O.C(S)CCCCC.[CH2:14]([S:20][CH:21]([S:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])[C:22]([OH:24])=[O:23])[CH2:15][CH2:16][CH2:17][CH2:18][CH3:19].[NH2:32][C:33]1[C:42]([S:43][CH3:44])=[CH:41][CH:40]=[C:39]2[C:34]=1[CH:35]=[CH:36][CH:37]=[N:38]2>>[CH2:26]([S:25][CH:21]([S:20][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])[C:22]([OH:24])=[O:23])[CH2:27][CH2:28][CH2:29][CH2:30][CH3:31].[CH3:44][S:43][C:42]1[C:33]([NH:32][C:22](=[O:24])[CH:21]([S:20][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])[S:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])=[C:34]2[C:39](=[CH:40][CH:41]=1)[N:38]=[CH:37][CH:36]=[CH:35]2

Participants

6

Reactant 4

HCID 6597Dichloroacetic AcidHCID 81061-HexanethiolHCID 103976605-Amino-6-methylthioquinolineHCID 19027775HCID 19027775, compound

Product 2

HCID 19027775HCID 19027775, compoundHCID 19027854HCID 19027854, compound

Procedure

2,2-Di (hexylthio) acetic acid was synthesized from dichloroacetic acid and hexanethiol using a procedure similar to that described in Example 1. 2, 2-Di(hexylthio)acetic acid and 5-amino-6-methylthioquinoline were coupled to give the title compound using the procedure described in Example 25.

Sources & evidence

ORD record
ord-91a8dba055054064b87ace64d64bf29c
Source dataset
uspto-grants-1994_11
Patent number
US05362878

Reaction notes

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