HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → N-[4,6-bis(dimethylamino)pyrimidin-5-yl]-cis-9-octadecenamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 4,6-Dichloro-5-nitropyrimidine | HCID 20312 | — |
| Reactant | Oleoyl chloride | HCID 5364783 | — |
| Reactant | 5-Amino-4,6-bis(dimethylamino)pyrimidine | HCID 15585370 | — |
| Product | N-[4,6-bis(dimethylamino)pyrimidin-5-yl]-cis-9-octadecenamide | HCID 67710051 | — |
Reaction Steps
5-Amino-4,6-bis(dimethylamino)pyrimidine (prepared by reacting commercially available 4,6-dichloro-5-nitro pyrimidine with excess dimethylamine followed by reduction of the nitro group according to the procedure of Jacobs et al., J. Am. Chem. Soc., 42, 2278 (1920)) was coupled with oleoyl chloride using the procedure described in Example 4 to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05362878 |
| Source dataset | uspto-grants-1994_11 |
| ORD ID | ord-f229e4f9f6be46ad85a4bab66cb0f49e |
| Source note | uspto-grants-1994_11 |