Oleoyl chloride → HCID 67710122, compound

HRID 2379635Notes

Reaction equation

HRID 2379635 reaction equation
[NH2:1][C:2]1[C:3]([N:10]([CH3:12])[CH3:11])=[N:4][CH:5]=[N:6][C:7]=1[S:8][CH3:9].[C:13](Cl)(=[O:31])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]/[CH:21]=[CH:22]\[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30]>>[CH3:12][N:10]([CH3:11])[C:3]1[C:2]([NH:1][C:13](=[O:31])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]/[CH:21]=[CH:22]\[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])=[C:7]([S:8][CH3:9])[N:6]=[CH:5][N:4]=1

Participants

3

Reactant 2

HCID 5364783Oleoyl chlorideHCID 12188120HCID 12188120, compound

Product 1

HCID 67710122HCID 67710122, compound

Procedure

5-Amino-4-dimethylamino-6-methylthiopyrimidine (prepared by reacting 5-amino-4-dimethylamino-6-chloropyrimidine with sodium thiomethoxide) was coupled with oleoyl chloride using the procedure described in Example 4 to give the title compound.

Sources & evidence

ORD record
ord-8fd6f3e2863147a4a53536760cba1763
Source dataset
uspto-grants-1994_11
Patent number
US05362878

Reaction notes

Loading…