4-Bromoisoquinolin-5-amine → HCID 53921682, 화합물

HRID 2379636노트

반응식

HRID 2379636 반응식
[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[C:4]([Br:12])=[CH:5][N:6]=[CH:7]2.[CH2:13]([CH:19]([CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[C:20](O)=[S:21])[CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]>>[Br:12][C:4]1[C:3]2[C:8](=[CH:9][CH:10]=[CH:11][C:2]=2[NH:1][C:20](=[S:21])[CH:19]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH:7]=[N:6][CH:5]=1

참가 물질

3

반응물 2

HCID 145800574-Bromoisoquinolin-5-amineHCID 178443126HCID 178443126, 화합물

생성물 1

HCID 53921682HCID 53921682, 화합물

실험 절차

5-Amino-4-bromoisoquinoline (prepared according to the process described by Gordon et al., J. Het. Chem., 4, 410 (1967)) was coupled with 2-hexylthiodecanoic acid (prepared by the procedures described in Examples 1 and 3) using the procedure described in Example 25 to give the title compound.

후처리

  1. customprepared by the procedures

출처 및 근거

ORD 기록
ord-6dcdb76540334395861da5f9c147720b
출처 데이터셋
uspto-grants-1994_11
특허 번호
US05362878

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