Oleoyl chloride → HCID 67710037, compound

HRID 2379638Notes

Reaction equation

HRID 2379638 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[C:4]([Br:12])=[CH:5][N:6]=[CH:7]2.[C:13](Cl)(=[O:31])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]/[CH:21]=[CH:22]\[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30]>>[Br:12][C:4]1[C:3]2[C:8](=[CH:9][CH:10]=[CH:11][C:2]=2[NH:1][C:13](=[O:31])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]/[CH:21]=[CH:22]\[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH:7]=[N:6][CH:5]=1

Participants

3

Reactant 2

HCID 5364783Oleoyl chlorideHCID 145800574-Bromoisoquinolin-5-amine

Product 1

HCID 67710037HCID 67710037, compound

Procedure

5-Amino-4-bromoisoquinoline (prepared according to the process described by Gordon et al., J. Het. Chem., 4, 410 (1967)) was coupled with oleoyl chloride using the procedure described in Example 4, to give the title compound.

Sources & evidence

ORD record
ord-3e49e0bcfc834a7dae6d6c327146c31b
Source dataset
uspto-grants-1994_11
Patent number
US05362878

Reaction notes

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