Dimethyl Sulfoxide → HCID 67820243, compound

Participants

Reaction Steps

0.75 g (0,025 mole) of 80% NaH is introduced into 8.2 g (0.02 mole) of 3-bromo-3,4-dihydro-2,2-dimethyl-6-(4-methylphenylsulfonyl)-2H-benzo[b]pyran-4-ol in 30 ml of dimethyl sulfoxide. After stirring at 20° for one hour, a further 0.75 g (0.025 mole) of 80% NaH and 1.9 ml (0,025 mole) of 2-pyrrolidone are added, and the mixture is stirred at 40° for 45 minutes and at 20° for 6 hours. It is introduced into ice-water and then the precipitate is filtered off with suction, dried and recrystallized from methanol several times.

Provenance & Evidence