HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonic Acid → 2-(Diaminomethyleneamino)-4-(2-ureidomethylthiazol-4-yl)thiazole methanesulfonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonic Acid | HCID 6395 | — |
| Reactant | 2-(Diaminomethyleneamino)-4-(2-ureidomethylthiazol-4-yl)thiazole | HCID 18953791 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(Diaminomethyleneamino)-4-(2-ureidomethylthiazol-4-yl)thiazole methanesulfonate | HCID 86748246 | 75.8% |
Reaction Steps
Methanesulfonic acid (2.16 g) was added to a suspension of 2-(diaminomethyleneamino)-4-(2-ureidomethylthiazol-4-yl)thiazole (3.19 g) in methanol (95 ml). The mixture was stirred at room temperature for 1 hour. The resulting precipitate was collected by filtration. Recrystallization from a mixture of acetonitrile and water afforded 2-(diaminomethyleneamino)-4-(2-ureidomethylthiazol-4-yl)thiazole methanesulfonate (3.2 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05364871 |
| Source dataset | uspto-grants-1994_11 |
| ORD ID | ord-8d40588791d9490bb29b35abbbbbb7cc |
| Source note | uspto-grants-1994_11 |