HCID 18987251, compound → 3,5-diphenylphenol

HRID 2380344Notes

Reaction equation

HRID 2380344 reaction equation
[C:1]1([C:7]2[CH:8]=[C:9]([O:19]C)[CH:10]=[C:11]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl.[NH+]1C=CC=CC=1>>[C:1]1([C:7]2[CH:8]=[C:9]([OH:19])[CH:10]=[C:11]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 18987251HCID 18987251, compoundHCID 21584435Pyridinium hydrochloride

Product 1

HCID 35546253,5-diphenylphenolYield 85%

Procedure

A mixture of 4.7 g of 3,5-diphenyl-anisole and 5.3 g of pyridinium hydrochloride was heated for 5 hours to 185° C. After cooling, the residue was partitioned between 100 cc of diethyl ether and 120 cc of water. The organic layer wes then washed with water, dried (Na2SO4) and evaporated. The resultant residue was suspended in 50 cc of n-hexane and filtered to give 3.75 g (85%) of 3,5-diphenyl-phenol as a white solid. (m.p.=97° C.)

Workup

  1. temperaturewas heated for 5 hours to 185° C
  2. temperatureAfter cooling
  3. customthe residue was partitioned between 100 cc of diethyl ether and 120 cc of water
  4. washThe organic layer wes then washed with water
  5. dry with materialdried (Na2SO4)
  6. customevaporated
  7. filtrationfiltered

Sources & evidence

ORD record
ord-a5616a605ab9402dad1700b2ec1c2bca
Source dataset
uspto-grants-1994_11
Patent number
US05366982

Reaction notes

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