4,6-Diphenyl-2-pyridone → 2,2-Dimethyl-6-[(4,6-diphenyl-2-pyridyl)oxy]hexanonitrile

Participants

Reaction Steps

The procedure in Example 4 is followed but using 4,6-diphenyl-2-pyridinone (6.3 g), 6-bromo-2,2-dimethylhexanonitrile (2.60 g) (prepared according to the method of M. Larcheveque et al., Bull. Soc. Chim. Fr., 1710 (1974)), silver carbonate (3.5 g) and toluene (300 cc). The product is purified by chromatography under pressure on silica gel (30-60 mm); eluent: n-hexane-ethyl acetate 9.5-0.5),yellowish solid. (m,p.=71° C.)

Provenance & Evidence