HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[2-(2-Methoxyethoxy)ethoxy]acetyl chloride → 11,22,33-Tris(benzyloxy)-12,15,23,26,34-pentaoxo-11,16,22,27,33-pentaaza-2,5,8,36,39,42-hexaoxatritetracontane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[2-(2-Methoxyethoxy)ethoxy]acetyl chloride | HCID 2759571 | — |
| Reactant | 11,22,33-Tris(benzyloxy)-12,15,23,26-tetraoxo-11,16,22,27,33-pentaaza-2,5,8-trioxatritriacontane | HCID 15101741 | — |
| Product | 11,22,33-Tris(benzyloxy)-12,15,23,26,34-pentaoxo-11,16,22,27,33-pentaaza-2,5,8,36,39,42-hexaoxatritetracontane | HCID 15101743 | 78% |
Reaction Steps
11,22,33-Tris(benzyloxy)-12,15,23,26,34-pentaoxo-11,16,22,27,33-pentaaza-2,5,8,36,39,42-hexaoxatritetracontane (23) was synthesized by reacting compound (21) (3.91 g, 4.60 mmol) with 3,6,9-trioxadecanoyl chloride [Helmann, supra] (NEt3 /CH2C12) to give 4.0 g (78%) of (23): NMR δ 1.17-1.78 (m, 12 H), 2.3-2.9 (m, 8 H), 3.04-3.37 (m, 10 H), 3.4-3.8 (m, 24 H), 4.21 (s, 2 H), 4.76 (s, 2 H), 4.81 (s, 2 H), 4.88 (s, 2 H), 6.17-6.37 (m, 2 H), 7.34 (s, 15 H). Analysis: (C53H79N5O14) C, H, N.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05367113 |
| Source dataset | uspto-grants-1994_11 |
| ORD ID | ord-35df8019d14c4f56bd0def06ebe5a772 |
| Source note | uspto-grants-1994_11 |