Water → HCID 67790522, compound

HRID 2380562Notes

Reaction equation

HRID 2380562 reaction equation
[CH:1]([C:4]1[C:5]([O:16][CH3:17])=[C:6]([CH:10]=[C:11]([CH:13]([CH3:15])[CH3:14])[CH:12]=1)[C:7]([OH:9])=[O:8])([CH3:3])[CH3:2].[OH-].[K+].O.O.O.O.O.O.O.O.S([O-])([O-])(=O)=O.[Zn+2:33]>CO>[CH:1]([C:4]1[C:5]([O:16][CH3:17])=[C:6]([CH:10]=[C:11]([CH:13]([CH3:15])[CH3:14])[CH:12]=1)[C:7]([O-:9])=[O:8])([CH3:3])[CH3:2].[Zn+2:33].[CH:1]([C:4]1[C:5]([O:16][CH3:17])=[C:6]([CH:10]=[C:11]([CH:13]([CH3:15])[CH3:14])[CH:12]=1)[C:7]([O-:9])=[O:8])([CH3:3])[CH3:2]

Participants

6

Reactant 4

HCID 962Water2×HCID 14797Potassium HydroxideHCID 62640Zinc Sulfate HeptahydrateHCID 189545872-Methoxy-3,5-di(propan-2-yl)benzoic acid

Product 1

HCID 67790522HCID 67790522, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Conditions

Temperature
60 °C

Procedure

Five parts of 3,5-diisopropyl-2-methoxybenzoic acid was dissolved in 80 parts of methyl alcohol, followed by the addition of an aqueous solution of 1.3 parts of 96% potassium hydroxide in 10 parts of water. The resulting mixture was heated to 60° C. An aqueous solution of 3.2 parts of zinc sulfate heptahydrate in 10 parts of water was dropped into the resulting mixture over a period of 15 minutes. After the completion of the dropping, the obtained mixture was stirred at that temperature for 2 hours, cooled to a room temperature and filtered to recover a white crystalline precipitate. This precipitate was dispersed in 60 parts of water, washed therewith and filtered. The obtained filter cake was dried to give 4.8 parts of a white crystal. The melting point thereof was 104 to 107° C.

Workup

  1. temperaturecooled to a room temperature
  2. filtrationfiltered
  3. customto recover a white crystalline precipitate
  4. additionThis precipitate was dispersed in 60 parts of water
  5. washwashed
  6. filtrationfiltered
  7. filtrationThe obtained filter cake
  8. customwas dried
  9. customto give 4.8 parts of a white crystal
  10. customthereof was 104 to 107° C.

Sources & evidence

ORD record
ord-be9b6bc0429c4fb4a61a7f4d75c9dabe
Source dataset
uspto-grants-1994_11
Patent number
US05368971

Reaction notes

Loading…