Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Propargyl bromide | HCID 7842 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 178508705 | HCID 178508705 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 24905249 | HCID 24905249 | — |
Reaction Steps
3-(naphthalen-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (50 mg, 0.21 mmol) was dissolved in DMF (1.5 mL) and K2CO3 (110 mg, 0.8 mmol) and propargylbromide were added. The reaction was heated to 60° C. overnight, then cooled to RT and poured into water (30 mL). The precipitate was collected by filtration. ESI-MS (M+H)+ m/z calcd 300.1, found 300.2
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08642604B2 |
|---|
| Source dataset | uspto-grants-2014_02 |
|---|
| ORD ID | ord-6bcb28f2570e4a48a921c88c69b48f51 |
|---|
| Source note | uspto-grants-2014_02 |
|---|
