tert-Butyl carbamate → HCID 59443050, compound

HRID 2380888Notes

Reaction equation

HRID 2380888 reaction equation
Cl[C:2]1[CH:11]=[C:10]2[C:5]([C:6]([C:15]3[CH:20]=[CH:19][C:18]([F:21])=[CH:17][CH:16]=3)=[C:7]([F:14])[C:8]([CH3:13])([CH3:12])[O:9]2)=[CH:4][CH:3]=1.[C:22](=[O:29])([O:24][C:25]([CH3:28])([CH3:27])[CH3:26])[NH2:23]>>[F:14][C:7]1[C:8]([CH3:13])([CH3:12])[O:9][C:10]2[C:5]([C:6]=1[C:15]1[CH:20]=[CH:19][C:18]([F:21])=[CH:17][CH:16]=1)=[CH:4][CH:3]=[C:2]([NH:23][C:22](=[O:29])[O:24][C:25]([CH3:28])([CH3:27])[CH3:26])[CH:11]=2

Participants

3

Reactant 2

HCID 77922tert-Butyl carbamateHCID 59443085HCID 59443085, compound

Product 1

HCID 59443050HCID 59443050, compound

Procedure

The compound obtained in (5) described above (125 mg) and tert-butyl carbamate (145 mg) were treated in the same manner as Reference Example 5(4) to give the titled compound (157 mg) as a brown viscous oil.

Sources & evidence

ORD record
ord-80225888158d4e6b92f9506f582bb5bc
Source dataset
uspto-grants-2012_09
Patent number
US08258131B2

Reaction notes

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